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Regardless of the use of multiple off label therapies, participants living with PBC globally had evidence of ongoing moderatesevere pruritus, underscoring the unmet need for a symptom-specific therapy targeting pruritus in PBC

Hernandez S et al (2008) ATP7B copper-regulated traffic and association with the tight junctions: copper excretion into the bile

Patients with mild COPD are typically excluded from clinical studies of COPD

Mechanobiology is an emerging field that combines biology and bioengineering to study how physical forces and changes in mechanical properties of cells contribute to cell development, differentiation, proliferation and disease

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